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Clozapine Tablets have been specifically formulated to be used for treatment of schizophrenia and are known to work by binding to serotonin & dopamine receptors. Clozapine has molecular weight of 326.83 g/mol with chemical formula C18H19ClN4 and shows bioavailability of 60 to 70%. Upon ingestion, chemical present in these tablets gets metabolized in liver with help CYP isozymes and excreted from kidney after elimination half life of 6 to 26 hours. Clozapine Tablets are considered as 5-HT2A subunit antagonist of serotonin receptor. They are atypical antipsychotic agents that are highly appreciated for having targeted mode of action with high effectiveness.
Clozapine is used in the treatment of schizophrenia (mental disorder in which patient interpret reality abnormally) and mania (abnormally elevated mood)
How it works
Clozapine works by modulating the action of certain chemical messengers in the brain that affects thoughts and mood.
Common side effects
Weight gain, Blurred vision, Constipation, Dizziness, Decreased white blood cell count, Increased saliva production, Increased heart rate, Sleepiness, Orthostatic hypotension (sudden lowering of blood pressure on standing)
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